Saturday, December 8, 2012

How does diabetes cause people to lose their foot?

Q. What is the relationship between a person having diabetes and the problems I see them having with their feet? My neighbor is constantly in the hospital for her foot because of her diabetes, why?

A. If you have diabetes, you may have an increased risk for developing foot sores, or ulcers. Foot ulcers are the most common reason for hospital stays for people with diabetes. It may take weeks or even several months for your foot ulcers to heal. Diabetic ulcers are often painless.
Major increase in mortality among diabetic patients, observed over the past 20 years is considered to be due to the development of macro and micro vascular complications, including failure of the wound healing process.
Diabetes mellitus neuropathy (the most common in the U.S. today, resulting in destruction of foot and ankle joints), with Charcot joints in 1/600-700 diabetics. Related to long-term poor glucose control.
Diabetes mellitus - causes between two and four times increased risk of PVD by causing endothelial and smooth muscle cell dysfunction in peripheral arteries. Diabetics account for up to 70% of nontraumatic amputations performed, and a known diabetic who smokes runs an approximately 30% risk of amputation within 5 years.


How does adaptation and acclimation play a role in gestational diabetes which occurs during pregnancy?
Q. Gestational diabetes occurs during pregnancy when the woman develops diabetes but loses it affect birth sometimes or when treated. I want to know how adaptation and acclimation play a part.

A. I got gestational diabetes when I was pregnant and my Dr. said the stress the baby causes on the body, causes you body to function as if you were in your 50s. The stress brings out any future conditions you may get. When the pregnancy was over I was diabetes free. But I will most likely get it again later if I do not control my diet, sugar intake and exercise regime for the rest of my life.


How does the development of diabetes directly relate to a feedback system?
Q. Paragraph on how Development of diabetes is directly related to feedback system, In your description describe how the feedback system works, organs, & molecules involved, also the direct effect of breakdown of a feedback system.

A. Does this bit of your homework really need to be explained? Glucose is high, pancreas releases insulin to bring it down. Glucose is low, pancreas releases glucagon to bring it up. It's a feedback system. Diabetes is when the insulin either can't be made, not enough can be made or the insulin doesn't work as well as it should and therefore the glucose level stays high.


What type of diabetes happens during pregnancy?
Q. Like the question states, what type of diabetes happens during pregnancy.
More importantly, why does the head of most babies are usually abnormally large after such a pregnancy?
I am more looking for an answer on why there heads are usually large after such a pregnancy.

It is a question my teacher has been asking and he wants to know why.

A. There is a slight increased risk of the fetus or newborn dying when the mother has gestational diabetes, but this risk is lowered with effective treatment and careful watching of the mother and fetus. High blood glucose levels often go back to normal after delivery. However, women with gestational diabetes should be watched closely after giving birth and at regular intervals to detect diabetes early.
Up to 40% of women with gestational diabetes develop full-blown diabetes within 5-10 years after delivery. The risk may be increased in obese women.
Please see the web pages for more details on Gestational diabetes.





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