Q. We have to write a paper in health class, and my topic is about a boy named Steve purposly trying to get type one, not type two, diabetes. Not my cup of tea, but I'll go with it.
So I'm asking you if there is a way, let me rephrase that, if it is even possible to try and get type one Diabetes.
So I'm asking you if there is a way, let me rephrase that, if it is even possible to try and get type one Diabetes.
A. Type 1 diabetes is a histocompatibility immunological disorder thought to be caused by beta cells of the pancreas present improper antigens to T cells. According to wikipedia the primary gene though to influence the poly-genetic trait that leads to type 1 diabetes is a macro histocompatibility complex (MHC II) gene in chromosome 6.
I'm not going to go through the process of antigen presentation to helper T cells and the activation of an immune response through the production of interleukin, however it is an important topic which you may want to familiarize yourself. An important consequence of this process is that if any point your body begins the process of antibody production for an antigen associated with the pancreases' beta cells, essentially type 1 diabetes could develop.
What are some scenarios in which one could induce such a response? Well the more likely one is that Steve gets a pancreas transplant. Since MHCs come in such a large variety in the human population, getting organs from other people will likely lead to a severe immune response, and eventual organ rejection. This is countered by immune-suppressants, taken throughout an organ recipients lifetime, and thus failure to take such medications could lead to failure of the pancreas and eventually lack of insulin production, characterized by type 1 diabetes.
Another scenario is that Steve takes a radioactive isotope, such as uranium, carves it into a knife and stabs his pancreas until cancer develops. (another source of radiation, or other carcinogenic substance could substitute this process).
Good luck on your paper. I hope this is enough to at least get your started.
I'm not going to go through the process of antigen presentation to helper T cells and the activation of an immune response through the production of interleukin, however it is an important topic which you may want to familiarize yourself. An important consequence of this process is that if any point your body begins the process of antibody production for an antigen associated with the pancreases' beta cells, essentially type 1 diabetes could develop.
What are some scenarios in which one could induce such a response? Well the more likely one is that Steve gets a pancreas transplant. Since MHCs come in such a large variety in the human population, getting organs from other people will likely lead to a severe immune response, and eventual organ rejection. This is countered by immune-suppressants, taken throughout an organ recipients lifetime, and thus failure to take such medications could lead to failure of the pancreas and eventually lack of insulin production, characterized by type 1 diabetes.
Another scenario is that Steve takes a radioactive isotope, such as uranium, carves it into a knife and stabs his pancreas until cancer develops. (another source of radiation, or other carcinogenic substance could substitute this process).
Good luck on your paper. I hope this is enough to at least get your started.
what is the differance between type 1 and type 2 diabetes?
Q. what is the differance between type one and type two diabetes. nick jonas has type 1 and on tv they always talk about type two. is one worse than 2 ? or are they both about the same?
A. Can I just add to what prophet1102 said.
Type 1
Type 1 diabetes develops if the body is unable to produce any insulin. This type of diabetes usually appears before the age of 40.
Type 1 diabetes is the least common of the two main types and accounts for between 5 � 15% of all people with diabetes.
Type 2
Type 2 diabetes develops when the body can still make some insulin, but not enough, or when the insulin that is produced does not work properly (known as insulin resistance).
In most cases this is linked with being overweight.
This type of diabetes usually appears in people over the age of 40, though in South Asian and African-Caribbean people often appears after the age of 25.
However, recently, more children are being diagnosed with the condition, some as young as seven.
Type 2 diabetes is the most common of the two main types and accounts for between 85 - 95% of all people with diabetes.
There are currently over 2.3 million people with diabetes in the UK and there are more than half a million people with diabetes who have the condition and don�t know it.
Type 1
Type 1 diabetes develops if the body is unable to produce any insulin. This type of diabetes usually appears before the age of 40.
Type 1 diabetes is the least common of the two main types and accounts for between 5 � 15% of all people with diabetes.
Type 2
Type 2 diabetes develops when the body can still make some insulin, but not enough, or when the insulin that is produced does not work properly (known as insulin resistance).
In most cases this is linked with being overweight.
This type of diabetes usually appears in people over the age of 40, though in South Asian and African-Caribbean people often appears after the age of 25.
However, recently, more children are being diagnosed with the condition, some as young as seven.
Type 2 diabetes is the most common of the two main types and accounts for between 85 - 95% of all people with diabetes.
There are currently over 2.3 million people with diabetes in the UK and there are more than half a million people with diabetes who have the condition and don�t know it.
Is flax seed oil good for type 2 diabetes?
Q. I know fish oil is bad because I have had bad experiences with it. Still, some people recommend fish oil for type two diabetes because many claim it helps maintain healthy glucose levels; however, that is not the case. So my question to you guys is, is flax seed oil good for type two diabetes, and if so, what are the benefits of taking it from someone with type two diabetes.
A. I can NOT recommend flax seed oil, but I do highly recommend ground flax seed as well as chia seeds for the many health benefits & nutrition. Due to the much higher amounts of antioxidants, chia seeds are not as fragile & do not require grinding to access nutrition.
Omega 3 fatty acids are PUFA�s (polyunsaturated fatty acids) & extremely fragile & start going rancid as soon as exposed to air. Polyunsaturated fatty acids are fine *in whole food sources* but when they are separated from a whole food, it exposes the fragile oils to air & causes them to quickly oxidize (go rancid). I do NOT recommend any polyunsaturated vegetable oils, oxidized oil creates free radical damage in the body.
There is a need to balance your Omega 6 fatty acids with Omega 3 (an individual ideally needs more Omega�3 than Omega�6) & ground flax seeds, chia seeds & cold water fish are really the only sources of Omega 3 that doesn't already have Omega 6 (that negates it's value). Walnuts & hemp seeds have Omega 3 but not more Omega 3 than Omega 6 to counter the excess Omega 6 already found in the diet.
The Omega 3 oils in ground flax seed are NOT the same Omega 3 oils found in cold water fish. Omega 3 oils from vegetation are ALA (alpha lipoic acid) & have health benefits but can NOT replace the DHA (docosahexaenoic acid) found only in cold water fish & some cold water algae. It "may" be possible for ALA to convert to EPA (eicosapentaenoic acid) & EPA to convert to DHA but the conversion process creates negligible amounts.
Another problem with ingesting �just� the oil, is that you are missing all the nutrition from the whole food source.
flax seeds are the highest natural source of lignans & that lignans are phytoestrogens. I have no clue what that translates to in real world. I think ground flax seeds (as well as chia seeds but not the separated oils) are healthy foods & highly recommend.
There is too much controversy over the internet & I don't think anyone really has a clue. (I know I don't)
here's a lil I found though from a highly reputable source -
Although phytoestrogens can also bind to estrogen receptors, their estrogenic activity is much weaker than endogenous estrogens, and they may actually block or antagonize the effects of estrogen in some tissues (8). Scientists are interested in the tissue-selective activities of phytoestrogens because anti-estrogenic effects in reproductive tissue could help reduce the risk of hormone-associated cancers (breast, uterine, ovarian, and prostate), while estrogenic effects in bone could help maintain bone density.
http://lpi.oregonstate.edu/infocenter/phytochemicals/lignans/
The main benefits of using ground flax seeds & other seeds for diabetics are that you replace carbohydrates with dietary fats. Too many carbohydrates from *any* source is not healthy for a diabetic, so a low carb, high fat diet is the only healthy option.
I'm a proponent of low carb diets & highly recommend a fat based diet to maximize health. All carbs >9g per hour trigger insulin & insulin doesn't allow other hormones to function when it dominates the bloodstream.
All carbs (even vegetables) are converted to sugar (glucose) in the body. Posted below is a fascinating interview with Dr.Richard Bernstein (the diabetes specialist & a type 1 diabetic) on youtube where he demonstrated how whole grain bread turned to glucose within one second in his mouth! He says the exact thing would happen with corn or an apple as well.
http://www.youtube.com/watch?v=3PZno7Nkuuw&feature=PlayList&p=72BB956FBFF0CD62&index=0&playnext=1
Dr.Richard Bernstein (the diabetes specialist & a type 1 diabetic) from his book, "Diabetes Solutions" pertinent chapters available to read online -
What if I, a physician, told you, a diabetic, to eat a diet that consisted of 60 percent sugar, 20 percent protein, and 20 percent fat? More than likely, you�d think I was insane. I�d think I was insane, and I would never make this suggestion to a diabetic (nor would I even make it to a nondiabetic). But this is just the diet the ADA recommended to diabetics for decades.
Whether you eat a piece of the nuttiest whole-grain bread, drink a Coke, or have mashed potatoes, the effect on blood glucose levels is essentially the same� blood sugar rises, fast. ... our saliva can break starches into the shorter chains on contact and then convert those into pure glucose.
With a number of important exceptions, carbohydrates, or foods derived primarily from plant sources that are starches, grains, and fruits, have the same ultimate effect on blood glucose levels that table sugar does.
http://www.diabetes-book.com/book/chapter9_3.shtml
Omega 3 fatty acids are PUFA�s (polyunsaturated fatty acids) & extremely fragile & start going rancid as soon as exposed to air. Polyunsaturated fatty acids are fine *in whole food sources* but when they are separated from a whole food, it exposes the fragile oils to air & causes them to quickly oxidize (go rancid). I do NOT recommend any polyunsaturated vegetable oils, oxidized oil creates free radical damage in the body.
There is a need to balance your Omega 6 fatty acids with Omega 3 (an individual ideally needs more Omega�3 than Omega�6) & ground flax seeds, chia seeds & cold water fish are really the only sources of Omega 3 that doesn't already have Omega 6 (that negates it's value). Walnuts & hemp seeds have Omega 3 but not more Omega 3 than Omega 6 to counter the excess Omega 6 already found in the diet.
The Omega 3 oils in ground flax seed are NOT the same Omega 3 oils found in cold water fish. Omega 3 oils from vegetation are ALA (alpha lipoic acid) & have health benefits but can NOT replace the DHA (docosahexaenoic acid) found only in cold water fish & some cold water algae. It "may" be possible for ALA to convert to EPA (eicosapentaenoic acid) & EPA to convert to DHA but the conversion process creates negligible amounts.
Another problem with ingesting �just� the oil, is that you are missing all the nutrition from the whole food source.
flax seeds are the highest natural source of lignans & that lignans are phytoestrogens. I have no clue what that translates to in real world. I think ground flax seeds (as well as chia seeds but not the separated oils) are healthy foods & highly recommend.
There is too much controversy over the internet & I don't think anyone really has a clue. (I know I don't)
here's a lil I found though from a highly reputable source -
Although phytoestrogens can also bind to estrogen receptors, their estrogenic activity is much weaker than endogenous estrogens, and they may actually block or antagonize the effects of estrogen in some tissues (8). Scientists are interested in the tissue-selective activities of phytoestrogens because anti-estrogenic effects in reproductive tissue could help reduce the risk of hormone-associated cancers (breast, uterine, ovarian, and prostate), while estrogenic effects in bone could help maintain bone density.
http://lpi.oregonstate.edu/infocenter/phytochemicals/lignans/
The main benefits of using ground flax seeds & other seeds for diabetics are that you replace carbohydrates with dietary fats. Too many carbohydrates from *any* source is not healthy for a diabetic, so a low carb, high fat diet is the only healthy option.
I'm a proponent of low carb diets & highly recommend a fat based diet to maximize health. All carbs >9g per hour trigger insulin & insulin doesn't allow other hormones to function when it dominates the bloodstream.
All carbs (even vegetables) are converted to sugar (glucose) in the body. Posted below is a fascinating interview with Dr.Richard Bernstein (the diabetes specialist & a type 1 diabetic) on youtube where he demonstrated how whole grain bread turned to glucose within one second in his mouth! He says the exact thing would happen with corn or an apple as well.
http://www.youtube.com/watch?v=3PZno7Nkuuw&feature=PlayList&p=72BB956FBFF0CD62&index=0&playnext=1
Dr.Richard Bernstein (the diabetes specialist & a type 1 diabetic) from his book, "Diabetes Solutions" pertinent chapters available to read online -
What if I, a physician, told you, a diabetic, to eat a diet that consisted of 60 percent sugar, 20 percent protein, and 20 percent fat? More than likely, you�d think I was insane. I�d think I was insane, and I would never make this suggestion to a diabetic (nor would I even make it to a nondiabetic). But this is just the diet the ADA recommended to diabetics for decades.
Whether you eat a piece of the nuttiest whole-grain bread, drink a Coke, or have mashed potatoes, the effect on blood glucose levels is essentially the same� blood sugar rises, fast. ... our saliva can break starches into the shorter chains on contact and then convert those into pure glucose.
With a number of important exceptions, carbohydrates, or foods derived primarily from plant sources that are starches, grains, and fruits, have the same ultimate effect on blood glucose levels that table sugar does.
http://www.diabetes-book.com/book/chapter9_3.shtml
How common is it to be misdiagnosed with diabetes?
Q. After completeing a glucose tolerance test with the results finding hypoglycemia, how can a doctor call it type two diabetes? How would glimiperide or glipizide help this condition? I guess I don't understand how these two medications work. Can anyone explain it? Thanks..
A. Before you let your doctor put you on medication, change your diet! My doctor wanted me to start on medication because my glucose was showing 129 on my blood work. 125 was the cutoff. We know people that have gone on medication only to become insulin dependant later on.
I have changed my diet, started excercising and my glucose levels are in check. I don't deny that I am in the first stages of becoming a type 2 diabetic but you shouldn't have to take medications right off the bat. Unless of course your blood sugar is over 300!
I don't want to be a nay sayer in the medical community but there is a lot of money to be made in medications, glucose strips ($1 a piece, glucometers are free of course), doctors visits. The glucose used to be 140 now it is 125. There is talk about lowering it even still! So if you are borderline the next blood test will have you pegged as a diabetic. Just image if 5 million more people become "diabetic" by looking at a blood test. Millions more people to give pills to, strips to buy, line some big drug pockets.
And once your pegged, forget it, your pegged for life. If you have some aspect of diabeties in your family like mine (dad had it), there is the heredity factor.
I can't stress enough about the diet and exercise portion. Monitor your glucose levels if you can for a couple of months and keep records on your food intake, weight and sugar levels. Present them to your doctor and then try a different course of action (medication) if you really need it.
I have changed my diet, started excercising and my glucose levels are in check. I don't deny that I am in the first stages of becoming a type 2 diabetic but you shouldn't have to take medications right off the bat. Unless of course your blood sugar is over 300!
I don't want to be a nay sayer in the medical community but there is a lot of money to be made in medications, glucose strips ($1 a piece, glucometers are free of course), doctors visits. The glucose used to be 140 now it is 125. There is talk about lowering it even still! So if you are borderline the next blood test will have you pegged as a diabetic. Just image if 5 million more people become "diabetic" by looking at a blood test. Millions more people to give pills to, strips to buy, line some big drug pockets.
And once your pegged, forget it, your pegged for life. If you have some aspect of diabeties in your family like mine (dad had it), there is the heredity factor.
I can't stress enough about the diet and exercise portion. Monitor your glucose levels if you can for a couple of months and keep records on your food intake, weight and sugar levels. Present them to your doctor and then try a different course of action (medication) if you really need it.
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