Monday, December 3, 2012

Can Anemia and Uremia develop from Diabetes Mellitus Type II?

Q. Can Anemia and Uremia develop from Diabetes Mellitus Type II?
If it's possible can someone explain it to me?
Thank you..

A. Anemia-induced fatigue is thought to be one of the major contributors to the uremic syndrome. Erythropoietin (EPO), a hormone necessary for red blood cell production in bone marrow, is produced by peritubular cells in the kidney in response to hypoxia (oxygen vital to tissue). Anemia associated with renal failure can be observed when the glomerular filtration rate (GFR) (a test to see how much fluid is filtered by the kidney) is less than 50 mL/min or when the serum creatinine is greater than 2 mg/dL. Diabetic patients may experience anemia with a GFR of less than 60 mL/min.

So is it possible yes and it is a major contributor to kidney failure.


What is the difference between diabetes mellitus and just diabetes?
Q. Is diabetes mellitus the specific name for type one diabetes or does mean both type one and two.

A. Diabetes mellitus, often simply referred to as diabetes�is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger).

There are three main types of diabetes:

Type 1 diabetes: results from the body's failure to produce insulin, and presently requires the person to inject insulin. (Also referred to as insulin-dependent diabetes mellitus, IDDM for short, and juvenile diabetes.)
Type 2 diabetes: results from insulin resistance, a condition in which cells fail to use insulin properly, sometimes combined with an absolute insulin deficiency. (Formerly referred to as non-insulin-dependent diabetes mellitus, NIDDM for short, and adult-onset diabetes.)
Gestational diabetes: is when pregnant women, who have never had diabetes before, have a high blood glucose level during pregnancy. It may precede development of type 2 DM.
Other forms of diabetes mellitus include congenital diabetes, which is due to genetic defects of insulin secretion, cystic fibrosis-related diabetes, steroid diabetes induced by high doses of glucocorticoids, and several forms of monogenic diabetes.

So simply diabetes mellitus is the specific medical name for all three main Diabetes type 1 , Diabetes type 2, Diabetes gestational (pregnancy related) and other forms that are listed above.

Hope this helps.


What is there to type 2 diabetes if its NOT high blood sugar?
Q. Because my mom told me that my doctor said I was pre-diabetic but my blood sugar/glucose levels were NORMAL. I just had a bit of an argument with my mom, with my main question being, "Well, isn't the main definition of type 2 diabetes "high blood sugar"?".

So if it isn't high blood sugar, then what is it? What else is there to type 2 diabetes? No one thought of getting an in-depth analysis from my doctor. My mom doesn't know when my next appointment is. Help?

A. The response from ~*~ is 100% incorrect, my friend, hence the thumbs down for her. No matter which type of diabetes mellitus you care to mention, it ALWAYS refers to hyperglycemia (higher than 'normal' blood glucose levels). (Diabetics CAN and DO suffer hypoglycemia, but this is only normally once they've been prescribed medications ... either oral or insulin ... to treat their diabetes.)

The ONLY way that your doctor would say that you were pre-diabetic is if your blood sugar level, at the time of testing, was higher than that of a non-diabetic. (S/he MAY suspect that you are at risk of type 2 diabetes based on your ethnicity (African Americans, Latin Americans, Asian, Native Americans, Pacific Islanders, Inuits, all carry a slightly higher risk of developing type 2. This is based, primarily, on genetics.)

If any of your close relatives have type 2 diabetes, puts you at increased risk of developing it yourself. This, again, is based on genetics.

If your mother developed gestational diabetes during the pregnancy whilst she was carrying you would also put you at slightly increased risk of developing type 2 diabetes.

If you have one or more siblings that have type 2 diabetes would also put you at increased risk of developing it too.

If you suffer with PCOS (Polycystic Ovary Syndrome), this will also put you at increased risk of developing type 2.

Certain types of medication(s) MAY also put you at increased risk of developing diabetes, though this could be type 1 as much as it could be type 1.

If you have a problem with alcohol abuse, this could also put you at increased risk of developing pancreatitis ... inflammation of the pancreas ... which could, in turn, lead to the development of diabetes.

If you've been diagnosed with Metabolic Syndrome (sometimes called Syndrome X), this can increase your chances of developing type 2 diabetes immensely.


What are the differences between type 1 diabetes mellitus and type 2 diabetes mellitus?
Q. I'd prefer the answer come from the Marieb Anatomy and Physiology text book. If you can answer this, please cite the page number(s) you referenced.

A. I don't have the book, but I do know the differences, if this helps:

type 1 diabetes happens when your pancreas cannot produce insulin. no one really knows why your pancreas cannot produce insulin, but some believe that it might have something to do with an autoimmune disease (your immune system attacking itself). type 1 diabetes is more prevalent among young people mostly between the ages of 7-16. Now, the reason you need insulin is so that your cells can pickup the sugar (glucose) from the bloodstream and transform it into energy. when insulin is not available, glucose levels stay high for long periods of time (high blood sugar). This in turn is dangerous because sugar starts taking water out of your cells, and because sugar can start scraping the blood vessels and eventually make them weaker.
type 2 diabetes is also a high blood sugar disease, but this is a different story. with type 2 diabetes, your pancreas works just fine, but your cells are resistant to insulin. type 2 diabetes is more prevalent in adults, and the causes are more genetic, or related to obesity, since obesity prevents the cells from utilizing the insulin.
hope this helps





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