Showing posts with label type ii diabetes. Show all posts
Showing posts with label type ii diabetes. Show all posts

Monday, December 10, 2012

what is the connection between type II diabetes and overheating?

Q. Id like to know what the connection is between type II diabetes and someone overheating. Ive looked all over the internet and all i find is info on diabetic neuropathy. Is there somewhere that explains scientifically/biologically what process goes on and how this happens? i'd really like to know !! if anyone has a website or SOMETHING i can be directed to....

A. Generally speaking, people with type II diabetes (esp when uncontrolled) have an increased blood glucose level. This not only causes water in the individual to be drawn out of their tissues, but it also causes an increase in water loss through increased urine production. Because water is the key to thermoregulation, when water is lost, so is our ability to manage our own temperature. This dehydration, probably along with a decrease in efficient circulation, is what causes overheating in many people with diabetes.


Which of the following statements about type II diabetes is false?
Q. Which of the following statements about type II diabetes is false?

Type II diabetes can be managed by monitoring blood glucose levels.
Type II diabetes can be managed with drugs that increase cellular responsiveness to insulin.
Type II diabetes can be managed by prescribed diets
Type II diabetes can be managed by insulin injections.

A. Type II diabetes can be managed by monitoring glucose levels - yes, monitoring helps management.
Type II diabetes can be managed with drugs that increase cellular responsiveness to insulin - some of the oral meds used perform that function.
Type II diabetes can be managed by prescribed diets - diet is an important part of diabetes management.
Type II diabetes can be managed by insulin injections - Many type II diabetics use insulin injections to help manage their disease. Here's some more information on that:
Insulin
Iantidiabetic drugs fail (i.e., the clinical benefit stops), insulin therapy may be necessary � usually in addition to oral medication therapy � to maintain normal or near normal glucose levels.[49][50]

Typical total daily dosage of insulin is 0.6 U/kg.[51] But, of course, best timing and indeed total amounts depend on diet (composition, amount, and timing) as well the degree of insulin resistance. More complicated estimations to guide initial dosage of insulin are:[52]

For men, [(fasting plasma glucose [mmol/liter]�5)x2] x (weight [kg]÷(14.3xheight [m])�height [m])
For women, [(fasting plasma glucose [mmol/liter]�5)x2] x (weight [kg]÷(13.2xheight [m])�height [m])
The initial insulin regimen are often chosen based on the patient's blood glucose profile.[53] Initially, adding nightly insulin to patients failing oral medications may be best.[54] Nightly insulin combines better with metformin than with sulfonylureas.[51] The initial dose of nightly insulin (measured in IU/d) should be equal to the fasting blood glucose level (measured in mmol/L). If the fasting glucose is reported in mg/dl, multiply by 0.05551 to convert to mmol/L.[55]

When nightly insulin is insufficient, choices include:

Premixed insulin with a fixed ratio of short and intermediate acting insulin; this tends to be more effective than long acting insulin, but is associated with increased hypoglycemia.[56][57].[58] Initial total daily dosage of biphasic insulin can be 10 units if the fasting plasma glucose values are less than 180 mg/dl or 12 units when the fasting plasma glucose is above 180 mg/dl".[57] A guide to titrating fixed ratio insulin is available.[53]
Long acting insulins such as insulin glargine and insulin detemir. A meta-analysis of randomized controlled trials by the Cochrane Collaboration found "only a minor clinical benefit of treatment with long-acting insulin analogues for patients with diabetes mellitus type 2".[59] More recently, a randomized controlled trial found that although long acting insulins were less effective, they were associated with reduced hypoglycemic episodes.[56]
Insulin Pump therapy in Type 2 diabetes is gradually becoming popular.In an original published study, in addition to reduction of blood sugars, there is evidence of profound benefits in resistant neuropathic pain and also improvements in sexual performance

so really, none of the statements are false


To prevent Type II diabetes, is it more important to avoid sugar and carbs, or to avoid fat?
Q. I understand that it is important to avoid both sugar/carbs and fat, to prevent insulin resistance (which then leads to Type II diabetes,) but which is more important?

A. What will make the most difference in preventing you from becoming full-blown diabetic is to lose weight. If you are obese, do what you need to do to get down into the overweight category. If you are overweight, do what you need to do to get into the normal category. That's not to say there aren't healthy-weight people that still have insulin resistance, but that helps most people.

As for food intake, fat doesn't affect your blood glucose because it has no carb. Carbs impact your blood glucose and need to be moderated. Doesn't matter if it's sugar, fruit, potatoes, bread, or milk - carbs are carbs. Keeping your carb intake at less than 30-35g per meal will not overload your body, and the insulin you produce should be able to metabolize that. Focus on lean meats and veggies as the bulk of your food. 30 minutes of exercise daily also makes a big difference, even if you divide it into two 15-minute brisk walks, because that increase in your metabolism continues throughout the day.


How dangerous is drinking and type II diabetes?
Q. My husband is a heavy drinker and was just diagnosed with type II diabetes. How dangerous is this? He is on Metformin currently, by the way.

I know he is choosing to do something very harmful to his body and I wish he would wise up...but I'd like to know the risks of this.

Thank you in advance.

A. Alcohol with diabetes is tricky. The alcohol can cause serious blood sugar lows if he does not eat adequately and limit his intake of alcohol. And the alcohol itself has 7 calories a gram, so some drinks are very high in calories, resulting in weight gain, which aggravates insulin resistance in Type II. That said, you are not the diabetes police. He is probably in denial to some extent. A diagnosis of diabetes in a previously healthy, or at least relatively healthy individual feels like a huge betrayal by your body. For your part, be supportive. Feed him according to his meal plan. Learn non-food, non alcohol rewards for celebrations, goals achieved, etc. Talk to a certified diabetic educator and/or a dietitian for a meal plan that allows for his lifestyle, likes, dislikes, and caloric needs. Exercise with him-even a walk after dinner is great. I recommend the Dlife.com website for recipes, information on current research and an online open forum for questions. Good Luck to both of you.





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what is the connection between type II diabetes and overheating?

Q. Id like to know what the connection is between type II diabetes and someone overheating. Ive looked all over the internet and all i find is info on diabetic neuropathy. Is there somewhere that explains scientifically/biologically what process goes on and how this happens? i'd really like to know !! if anyone has a website or SOMETHING i can be directed to....

A. Generally speaking, people with type II diabetes (esp when uncontrolled) have an increased blood glucose level. This not only causes water in the individual to be drawn out of their tissues, but it also causes an increase in water loss through increased urine production. Because water is the key to thermoregulation, when water is lost, so is our ability to manage our own temperature. This dehydration, probably along with a decrease in efficient circulation, is what causes overheating in many people with diabetes.


Which of the following statements about type II diabetes is false?
Q. Which of the following statements about type II diabetes is false?

Type II diabetes can be managed by monitoring blood glucose levels.
Type II diabetes can be managed with drugs that increase cellular responsiveness to insulin.
Type II diabetes can be managed by prescribed diets
Type II diabetes can be managed by insulin injections.

A. Type II diabetes can be managed by monitoring glucose levels - yes, monitoring helps management.
Type II diabetes can be managed with drugs that increase cellular responsiveness to insulin - some of the oral meds used perform that function.
Type II diabetes can be managed by prescribed diets - diet is an important part of diabetes management.
Type II diabetes can be managed by insulin injections - Many type II diabetics use insulin injections to help manage their disease. Here's some more information on that:
Insulin
Iantidiabetic drugs fail (i.e., the clinical benefit stops), insulin therapy may be necessary � usually in addition to oral medication therapy � to maintain normal or near normal glucose levels.[49][50]

Typical total daily dosage of insulin is 0.6 U/kg.[51] But, of course, best timing and indeed total amounts depend on diet (composition, amount, and timing) as well the degree of insulin resistance. More complicated estimations to guide initial dosage of insulin are:[52]

For men, [(fasting plasma glucose [mmol/liter]�5)x2] x (weight [kg]÷(14.3xheight [m])�height [m])
For women, [(fasting plasma glucose [mmol/liter]�5)x2] x (weight [kg]÷(13.2xheight [m])�height [m])
The initial insulin regimen are often chosen based on the patient's blood glucose profile.[53] Initially, adding nightly insulin to patients failing oral medications may be best.[54] Nightly insulin combines better with metformin than with sulfonylureas.[51] The initial dose of nightly insulin (measured in IU/d) should be equal to the fasting blood glucose level (measured in mmol/L). If the fasting glucose is reported in mg/dl, multiply by 0.05551 to convert to mmol/L.[55]

When nightly insulin is insufficient, choices include:

Premixed insulin with a fixed ratio of short and intermediate acting insulin; this tends to be more effective than long acting insulin, but is associated with increased hypoglycemia.[56][57].[58] Initial total daily dosage of biphasic insulin can be 10 units if the fasting plasma glucose values are less than 180 mg/dl or 12 units when the fasting plasma glucose is above 180 mg/dl".[57] A guide to titrating fixed ratio insulin is available.[53]
Long acting insulins such as insulin glargine and insulin detemir. A meta-analysis of randomized controlled trials by the Cochrane Collaboration found "only a minor clinical benefit of treatment with long-acting insulin analogues for patients with diabetes mellitus type 2".[59] More recently, a randomized controlled trial found that although long acting insulins were less effective, they were associated with reduced hypoglycemic episodes.[56]
Insulin Pump therapy in Type 2 diabetes is gradually becoming popular.In an original published study, in addition to reduction of blood sugars, there is evidence of profound benefits in resistant neuropathic pain and also improvements in sexual performance

so really, none of the statements are false


To prevent Type II diabetes, is it more important to avoid sugar and carbs, or to avoid fat?
Q. I understand that it is important to avoid both sugar/carbs and fat, to prevent insulin resistance (which then leads to Type II diabetes,) but which is more important?

A. What will make the most difference in preventing you from becoming full-blown diabetic is to lose weight. If you are obese, do what you need to do to get down into the overweight category. If you are overweight, do what you need to do to get into the normal category. That's not to say there aren't healthy-weight people that still have insulin resistance, but that helps most people.

As for food intake, fat doesn't affect your blood glucose because it has no carb. Carbs impact your blood glucose and need to be moderated. Doesn't matter if it's sugar, fruit, potatoes, bread, or milk - carbs are carbs. Keeping your carb intake at less than 30-35g per meal will not overload your body, and the insulin you produce should be able to metabolize that. Focus on lean meats and veggies as the bulk of your food. 30 minutes of exercise daily also makes a big difference, even if you divide it into two 15-minute brisk walks, because that increase in your metabolism continues throughout the day.


How dangerous is drinking and type II diabetes?
Q. My husband is a heavy drinker and was just diagnosed with type II diabetes. How dangerous is this? He is on Metformin currently, by the way.

I know he is choosing to do something very harmful to his body and I wish he would wise up...but I'd like to know the risks of this.

Thank you in advance.

A. Alcohol with diabetes is tricky. The alcohol can cause serious blood sugar lows if he does not eat adequately and limit his intake of alcohol. And the alcohol itself has 7 calories a gram, so some drinks are very high in calories, resulting in weight gain, which aggravates insulin resistance in Type II. That said, you are not the diabetes police. He is probably in denial to some extent. A diagnosis of diabetes in a previously healthy, or at least relatively healthy individual feels like a huge betrayal by your body. For your part, be supportive. Feed him according to his meal plan. Learn non-food, non alcohol rewards for celebrations, goals achieved, etc. Talk to a certified diabetic educator and/or a dietitian for a meal plan that allows for his lifestyle, likes, dislikes, and caloric needs. Exercise with him-even a walk after dinner is great. I recommend the Dlife.com website for recipes, information on current research and an online open forum for questions. Good Luck to both of you.





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Sunday, December 9, 2012

what is the connection between type II diabetes and overheating?

Q. Id like to know what the connection is between type II diabetes and someone overheating. Ive looked all over the internet and all i find is info on diabetic neuropathy. Is there somewhere that explains scientifically/biologically what process goes on and how this happens? i'd really like to know !! if anyone has a website or SOMETHING i can be directed to....

A. Generally speaking, people with type II diabetes (esp when uncontrolled) have an increased blood glucose level. This not only causes water in the individual to be drawn out of their tissues, but it also causes an increase in water loss through increased urine production. Because water is the key to thermoregulation, when water is lost, so is our ability to manage our own temperature. This dehydration, probably along with a decrease in efficient circulation, is what causes overheating in many people with diabetes.


Which of the following statements about type II diabetes is false?
Q. Which of the following statements about type II diabetes is false?

Type II diabetes can be managed by monitoring blood glucose levels.
Type II diabetes can be managed with drugs that increase cellular responsiveness to insulin.
Type II diabetes can be managed by prescribed diets
Type II diabetes can be managed by insulin injections.

A. Type II diabetes can be managed by monitoring glucose levels - yes, monitoring helps management.
Type II diabetes can be managed with drugs that increase cellular responsiveness to insulin - some of the oral meds used perform that function.
Type II diabetes can be managed by prescribed diets - diet is an important part of diabetes management.
Type II diabetes can be managed by insulin injections - Many type II diabetics use insulin injections to help manage their disease. Here's some more information on that:
Insulin
Iantidiabetic drugs fail (i.e., the clinical benefit stops), insulin therapy may be necessary � usually in addition to oral medication therapy � to maintain normal or near normal glucose levels.[49][50]

Typical total daily dosage of insulin is 0.6 U/kg.[51] But, of course, best timing and indeed total amounts depend on diet (composition, amount, and timing) as well the degree of insulin resistance. More complicated estimations to guide initial dosage of insulin are:[52]

For men, [(fasting plasma glucose [mmol/liter]�5)x2] x (weight [kg]÷(14.3xheight [m])�height [m])
For women, [(fasting plasma glucose [mmol/liter]�5)x2] x (weight [kg]÷(13.2xheight [m])�height [m])
The initial insulin regimen are often chosen based on the patient's blood glucose profile.[53] Initially, adding nightly insulin to patients failing oral medications may be best.[54] Nightly insulin combines better with metformin than with sulfonylureas.[51] The initial dose of nightly insulin (measured in IU/d) should be equal to the fasting blood glucose level (measured in mmol/L). If the fasting glucose is reported in mg/dl, multiply by 0.05551 to convert to mmol/L.[55]

When nightly insulin is insufficient, choices include:

Premixed insulin with a fixed ratio of short and intermediate acting insulin; this tends to be more effective than long acting insulin, but is associated with increased hypoglycemia.[56][57].[58] Initial total daily dosage of biphasic insulin can be 10 units if the fasting plasma glucose values are less than 180 mg/dl or 12 units when the fasting plasma glucose is above 180 mg/dl".[57] A guide to titrating fixed ratio insulin is available.[53]
Long acting insulins such as insulin glargine and insulin detemir. A meta-analysis of randomized controlled trials by the Cochrane Collaboration found "only a minor clinical benefit of treatment with long-acting insulin analogues for patients with diabetes mellitus type 2".[59] More recently, a randomized controlled trial found that although long acting insulins were less effective, they were associated with reduced hypoglycemic episodes.[56]
Insulin Pump therapy in Type 2 diabetes is gradually becoming popular.In an original published study, in addition to reduction of blood sugars, there is evidence of profound benefits in resistant neuropathic pain and also improvements in sexual performance

so really, none of the statements are false


To prevent Type II diabetes, is it more important to avoid sugar and carbs, or to avoid fat?
Q. I understand that it is important to avoid both sugar/carbs and fat, to prevent insulin resistance (which then leads to Type II diabetes,) but which is more important?

A. What will make the most difference in preventing you from becoming full-blown diabetic is to lose weight. If you are obese, do what you need to do to get down into the overweight category. If you are overweight, do what you need to do to get into the normal category. That's not to say there aren't healthy-weight people that still have insulin resistance, but that helps most people.

As for food intake, fat doesn't affect your blood glucose because it has no carb. Carbs impact your blood glucose and need to be moderated. Doesn't matter if it's sugar, fruit, potatoes, bread, or milk - carbs are carbs. Keeping your carb intake at less than 30-35g per meal will not overload your body, and the insulin you produce should be able to metabolize that. Focus on lean meats and veggies as the bulk of your food. 30 minutes of exercise daily also makes a big difference, even if you divide it into two 15-minute brisk walks, because that increase in your metabolism continues throughout the day.


How dangerous is drinking and type II diabetes?
Q. My husband is a heavy drinker and was just diagnosed with type II diabetes. How dangerous is this? He is on Metformin currently, by the way.

I know he is choosing to do something very harmful to his body and I wish he would wise up...but I'd like to know the risks of this.

Thank you in advance.

A. Alcohol with diabetes is tricky. The alcohol can cause serious blood sugar lows if he does not eat adequately and limit his intake of alcohol. And the alcohol itself has 7 calories a gram, so some drinks are very high in calories, resulting in weight gain, which aggravates insulin resistance in Type II. That said, you are not the diabetes police. He is probably in denial to some extent. A diagnosis of diabetes in a previously healthy, or at least relatively healthy individual feels like a huge betrayal by your body. For your part, be supportive. Feed him according to his meal plan. Learn non-food, non alcohol rewards for celebrations, goals achieved, etc. Talk to a certified diabetic educator and/or a dietitian for a meal plan that allows for his lifestyle, likes, dislikes, and caloric needs. Exercise with him-even a walk after dinner is great. I recommend the Dlife.com website for recipes, information on current research and an online open forum for questions. Good Luck to both of you.





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Saturday, December 1, 2012

Can you be discharged from air force reserves if you have type II diabetes?

Q. Have served for 20 years in Air Force reserves. I have type II diabetes. It is controlled through medication daily. Will I be discharged?

A. Maybe; if your job requires you to be on flying status another factor is if it requires world-wide-duty eligibility. E-mail me and I can give you a couple of other factors that might have an impact on this.


Is type II diabetes reversable if your not massively over weight?
Q. Is type II diabetes reversable if your not massively over weight (like over weight like 5 or 10 pounds over?

I thought it was my understanding that all types of diabetes are reversable, but a friend of mine who was recently diagnosed said her type II is not because she isn't massively over weight.

I would like to know who is correct and is it reversable?

A. According to my diabetics instructor in pharmacy school, type 2 diabetes actually is reversible in some patients. Non-esterified fatty acids (NEFAs--what you get when you're overweight) promote insulin resistance, which is what actually causes the glucose intolerance that is seen in type 2 diabetics.

Diet and exercise alone can result in weight loss which will in turn decrease insulin resistance as well as possibly effect a 0.25-2.9% decrease in A1C (average plasma glucose levels over a 2-4 month time span). This instructor (who is a pharmacist) has even said in class that he has known some patients that were able to stop taking their diabetic medications (and still have normal blood glucose levels) just by diet/exercising and losing weight.

Type 1 diabetes unfortunately cannot be reversed. Islet cell transplantation is an option, unfortunately then you most likely have to deal with immunosuppressant meds, which is just as bad (if not worse) than insulin. Although there has been a report of an islet cell transplant patient not taking immunosuppressant meds and not having complications/rejection issues because of that. So, this therapy may be more popular if no immunosuppression is needed.


Can I get back into the Navy after being diagnosed with Type II diabetes?
Q. I was in the Navy for 15 years. I got out and have spent the last few years working in the civilian world. I'd liked to go back into the Navy and finish my 20 years.

My problem is that I was diagnosed with Type II diabetes about 2 years ago.

Can I still get back in or is it a deal breaker?

A. I believe it's a deal breaker, unfortunately. If you were enlisted while you were diagnosed, they might have just switched you to a desk job, but still lots of people get discharged for it. It's worth asking about, but last I heard they still turn people away for both Type 1 and Type 2 diabetes.


Why do insulin injections treat type II diabetes?
Q. I'm studying for my cellular biology exam, and my textbook says Type II diabetes develops when cell-surface receptors stop functioning normally and thus can't receive the message being sent by insulin to import glucose from the bloodstream. So why is diabetes treated with insulin injections if the problem isn't insulin production but rather the cell's inability to recognize insulin? I feel like there shouldn't be any effect if the cell isn't recognizing insulin in the first place.

A. What you're describing is known as insulin resistance. Insulin resistance doesn't stop the cells from using insulin entirely. In fact, a person in the early stages of insulin resistance can maintain normal blood sugar because the pancreas responds by producing more insulin. Insulin resistance simply makes it more difficult for insulin--injected or natural--to work effectively. If an insulin-resistant person injects enough insulin, eventually blood sugar will go down. People with insulin resistance do typically have to inject more than an insulin-sensitive Type 1 diabetic.

Also, over time, many insulin-resistant Type 2s become insulin deficient. The beta cells in the pancreas die and do not get regenerated, so the pancreas loses some of its insulin-producing capacity. At this point, eating a low-carbohydrate diet, exercising, and taking oral medications that either improve insulin sensitivity or stimulate the pancreas to make more insulin won't work, and injected insulin is the only answer. There's some evidence that by the time a Type 2 is diagnosed, over 50% of his beta cells are lost, meaning that the problem is no longer just insulin resistance.





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